User:Pothosjoy3/Cancer-related fatigue

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“Cancer-related fatigue is a symptom of fatigue that is experienced by nearly all cancer patients”. [1]

“Some management strategies may help all patients and could be supported by the work of an Occupational Therapist. These include scheduling high-priority tasks during the patient's best time of day, using labor-saving devices, delegating tasks to caregivers, and avoiding unimportant activities, so that the patient will have more energy available for other activities”. [2]

“Pain, difficulty breathing, and fatigue form a common symptom cluster. Fatigue often increases as patients with advanced cancer approach death. As a result, people who are dying often sleep much more than a healthy person”. [3][4]

While antidepressants are ineffective at reducing fatigue in non-depressed cancer patients, psychostimulants such as methylphenidate and amphetamines may reduce fatigue in some patients. [ADD ONTO THIS EXPLAINING THE DIFFERENCE FOR THOSE WHO DO FACE EXACERBATED SYMPTOMS DUE TO MENTAL HEALTH CHALLENGES AND THE SCREENING FOR THIS]

The findings of a study conducted by researchers from reputable universities in the UK indicate that methylphenidate may be effective in the management of CRF (Cancer Related Fatigue). If methylphenidate were to be used in patients with CRF, it would be prudent to restrict its use to patients with advanced disease or for short-term use in patients on active treatment. The clear advantage of methylphenidate in cancer is its rapid onset of action within 24-48 hours, and so the drug can be discontinued if ineffective. [5]

Added:

Forms of exercise that have been proven to be most effective are more aerobic exercises such as walking, running, cycling, and swimming. These forms of activity can be done at various levels of intensity and have been proven as an effective way of improving QOL for cancer patients.



Patients who are not at the end of life may benefit from physical exercise or physical therapy. Engaging in physical activity may reduce fatigue.[6][7][8][9] Forms of exercise that have been proven to be most effective are more aerobic exercise such as walking, running, cycling, and swimming. These forms of activity can be done at all different levels of intensity and have been proven as an effective way of improving QOL for cancer patients.[10]

While antidepressants are ineffective at reducing fatigue in non-depressed cancer patients, psychostimulants such as methylphenidate and amphetamines may reduce fatigue in some patients.[6][11][12][13][14]


oftentimes cancer patients experience cancer-related fatigue

Secondary sources:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647480/

https://www.cancer.gov/about-cancer/treatment/side-effects/fatigue

https://www.cancer.org/cancer/managing-cancer/side-effects/fatigue/managing-cancer-related-fatigue.html

https://www.mskcc.org/cancer-care/patient-education/managing-related-fatigue

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  1. ^ Hofman, Maarten; Ryan, Julie L.; Figueroa-Moseley, Colmar D.; Jean-Pierre, Pascal; Morrow, Gary R. (2007-05-01). "Cancer-Related Fatigue: The Scale of the Problem". The Oncologist. 12 (S1): 4–10. doi:10.1634/theoncologist.12-s1-4. ISSN 1083-7159.
  2. ^ Wallis, Amy; Meredith, Pamela; Stanley, Mandy (2020-04). "Cancer care and occupational therapy: A scoping review". Australian Occupational Therapy Journal. 67 (2) (published November 6, 2019): 172–194. doi:10.1111/1440-1630.12633. ISSN 0045-0766. {{cite journal}}: Check date values in: |date= (help)
  3. ^ Lin, Shuanglan; Chen, Yanhan; Yang, Liu; Zhou, Jianrong (2013-05). "Pain, fatigue, disturbed sleep and distress comprised a symptom cluster that related to quality of life and functional status of lung cancer surgery patients". Journal of Clinical Nursing. 22 (9–10): 1281–1290. doi:10.1111/jocn.12228. ISSN 0962-1067. {{cite journal}}: Check date values in: |date= (help)
  4. ^ Klasson, Caritha; Helde Frankling, Maria; Lundh Hagelin, Carina; Björkhem-Bergman, Linda (2021-01). "Fatigue in Cancer Patients in Palliative Care—A Review on Pharmacological Interventions". Cancers. 13 (5): 985. doi:10.3390/cancers13050985. ISSN 2072-6694. PMC 7956665. PMID 33652866. {{cite journal}}: Check date values in: |date= (help)CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
  5. ^ Minton, Ollie; Richardson, Alison; Sharpe, Michael; Hotopf, Matthew; Stone, Patrick C. (2011-04). "Psychostimulants for the Management of Cancer-Related Fatigue: A Systematic Review and Meta-Analysis". Journal of Pain and Symptom Management. 41 (4): 761–767. doi:10.1016/j.jpainsymman.2010.06.020. ISSN 0885-3924. {{cite journal}}: Check date values in: |date= (help); no-break space character in |title= at position 39 (help)
  6. ^ a b "NCCN Clinical Practice Guidelines in Oncology: Cancer-Related Fatigue" (PDF) (Version 1.2010 ed.). National Comprehensive Cancer Network. 22 January 2010.
  7. ^ Jose Stephy, Diwan Sanjay Kumar. Effect of standardized exercise program on reported fatigue in patients of cancer receiving chemotherapy. Clinical Cancer Investigation Journal 3(5): 373-376
  8. ^ Mishra, Shiraz I.; Scherer, Roberta W.; Geigle, Paula M.; Berlanstein, Debra R.; Topaloglu, Ozlem; Gotay, Carolyn C.; Snyder, Claire (2012-08-15). "Exercise interventions on health-related quality of life for cancer survivors". The Cochrane Database of Systematic Reviews. 2012 (8): CD007566. doi:10.1002/14651858.CD007566.pub2. ISSN 1469-493X. PMC 7387117. PMID 22895961.
  9. ^ Cramp F, Byron-Daniel J (November 2012). "Exercise for the management of cancer-related fatigue in adults". The Cochrane Database of Systematic Reviews. 11 (11): CD006145. doi:10.1002/14651858.CD006145.pub3. PMC 8480137. PMID 23152233.
  10. ^ Thompson, Paul D.; Arena, Ross; Riebe, Deborah; Pescatello, Linda S. (July/August 2013). "ACSM's New Preparticipation Health Screening Recommendations from ACSM's Guidelines for Exercise Testing and Prescription, Ninth Edition". Current Sports Medicine Reports. 12 (4): 215. doi:10.1249/JSR.0b013e31829a68cf. ISSN 1537-8918. {{cite journal}}: Check date values in: |date= (help)
  11. ^ Breitbart W, Alici Y (August 2010). "Psychostimulants for cancer-related fatigue". Journal of the National Comprehensive Cancer Network. 8 (8): 933–942. doi:10.6004/jnccn.2010.0068. PMID 20870637.
  12. ^ Minton O, Richardson A, Sharpe M, Hotopf M, Stone PC (April 2011). "Psychostimulants for the management of cancer-related fatigue: a systematic review and meta-analysis". Journal of Pain and Symptom Management. 41 (4): 761–767. doi:10.1016/j.jpainsymman.2010.06.020. PMID 21251796.
  13. ^ Gong S, Sheng P, Jin H, He H, Qi E, Chen W, et al. (2014). "Effect of methylphenidate in patients with cancer-related fatigue: a systematic review and meta-analysis". PLOS ONE. 9 (1): e84391. Bibcode:2014PLoSO...984391G. doi:10.1371/journal.pone.0084391. PMC 3885551. PMID 24416225.
  14. ^ Yennurajalingam S, Bruera E (2014). "Review of clinical trials of pharmacologic interventions for cancer-related fatigue: focus on psychostimulants and steroids". Cancer Journal. 20 (5): 319–324. doi:10.1097/PPO.0000000000000069. PMID 25299141. S2CID 29351114.