Template
:
Ligand-gated ion channels
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v
t
e
Ion channel
,
cell surface receptor
:
ligand-gated ion channels
Cys-loop receptors
5-HT/serotonin
5-HT
3
A
B
C
D
E
GABA
GABA
A
α
1
α
2
α
3
α
4
α
5
α
6
β
1
β
2
β
3
γ
1
γ
2
γ
3
δ
ε
π
θ
GABA
A
-ρ
ρ
1
ρ
2
ρ
3
Glycine
α
1
α
2
α
3
α
4
β
Nicotinic acetylcholine
monomers:
α1
α2
α3
α4
α5
α6
α7
α9
α10
β1
β2
β3
β4
δ
ε
pentamers:
(α3)
2
(β4)
3
(α4)
2
(β2)
3
(α7)
5
(α1)
2
(β4)
3
- Ganglion type
(α1)
2
β1δε - Muscle type
Zinc
Zinc-activated
Ionotropic
glutamates
Ligand-gated only
AMPA
(
1
2
3
4
)
Kainate
1
2
3
4
5
Voltage- and ligand-gated
NMDA
1
2A
2B
2C
2D
3A
3B
L1A
L1B
‘Orphan’
GluD
δ
1
δ
2
ATP
-
gated channels
Purinergic receptors
P2X
1
2
3
4
5
6
7
Category
:
Cell surface receptor templates
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