User contributions for CatPath
A user with 2,626 edits. Account created on 22 June 2011.
18 April 2024
- 00:0400:04, 18 April 2024 diff hist −3 Governorship of Ronald Reagan →Tax cuts: This section shouldn't be titled "Tax cuts" since Reagan raised taxes
30 January 2023
- 03:1903:19, 30 January 2023 diff hist +351 Talk:Applied behavior analysis →Request for Comment: dealing with controversies: No advocacy groups.
- 02:5302:53, 30 January 2023 diff hist +866 Talk:Applied behavior analysis →Request for Comment: dealing with controversies: More on survey
- 00:1500:15, 30 January 2023 diff hist +397 Talk:Applied behavior analysis →Request for Comment: dealing with controversies: Re: failure to consider adverse effects; forgot to mention a study that actually mentions ABA
29 January 2023
- 23:4623:46, 29 January 2023 diff hist +1,845 Talk:Applied behavior analysis →Request for Comment: dealing with controversies: Some poor sourcing in longer version
8 January 2023
- 17:4617:46, 8 January 2023 diff hist −436 Spirochaete →Pathogenicity: Manual revert. There’s already a nice secondary source to support the claim. Why are we adding an obscure primary source?
13 December 2022
- 08:2008:20, 13 December 2022 diff hist −116 Discrete trial training Unsourced. They don’t use DTT. Tag: Undo
25 November 2022
- 13:5413:54, 25 November 2022 diff hist −555 Treponema pallidum →top: Manual revert. Bovine digital dermatitis is associated with other species of Treponema, not Treponema pallium.
22 November 2022
- 20:5720:57, 22 November 2022 diff hist +10 Leptospira interrogans →top: Replaced old primary source with a more recent secondary source.
- 20:1520:15, 22 November 2022 diff hist +371 Leptospira interrogans →Molecular pathogenesis: Add secondary source for claim that LipL32 is subsurface since this is controversial. LipL32 binds to ECM components in vitro. There's a whole section about LipL32 in the source.
- 20:0020:00, 22 November 2022 diff hist +221 Leptospira interrogans →Genomics: This is why you don't use old primary sources. According to a review article that is now cited, the Lai strain from the 2003 paper was resequenced to correct sequencing errors and for reannotation. Corrected the gene counts and added other tidbits of information from the review paper.
- 19:3319:33, 22 November 2022 diff hist −50 Leptospira interrogans →top: Why the focus on inadequate sewage treatment? The CDC source cited at the end of the next sentence talks a lot about flooding also being a cause.
- 19:3019:30, 22 November 2022 diff hist −623 Leptospira interrogans →top: Replaced really old primary source with recent secondary source that gives more accurate information about shape of ends of Leptospira. Please don't use the introductions of primary research articles as sources.
- 19:2619:26, 22 November 2022 diff hist −39 Leptospira interrogans →top: Leptospira is incubated in laboratory cultures at 28-30C. This doesn't mean the bacteria are found in nature at those temperatures, and no source claims this.
17 November 2022
- 19:4619:46, 17 November 2022 diff hist +299 Leptospira interrogans →Morphology: Ends of Leptospira can also be spiral. They aren't only hooked. Moved ref since it supports the first two sentences.
- 19:4119:41, 17 November 2022 diff hist +18 Leptospira interrogans →Biology and Biochemistry: Replaced unnecessary jargon ("polar") with easier wording
- 19:3919:39, 17 November 2022 diff hist −386 Leptospira interrogans →Morphology: Replaced a two-decade old primary source with secondary source.
12 November 2022
- 22:1222:12, 12 November 2022 diff hist −6 Leptospira interrogans →Molecular pathogenesis: It's a single study, and it's not recent. Italicized more gene names.
- 22:0922:09, 12 November 2022 diff hist +12 Leptospira interrogans →Molecular pathogenesis: Italicize gene names
- 22:0722:07, 12 November 2022 diff hist −98 Leptospira interrogans →Genomics: Removed image, which was lifted from a journal article that isn't mentioned anywhere, either in the article or on the image page.
- 21:1621:16, 12 November 2022 diff hist −62 Leptospira interrogans →Humans: Actually, the sentence I was going to add back is already there. Reworded. Removed oxytetracycline because I don't see it in the CDC source.
- 21:1321:13, 12 November 2022 diff hist −7,077 Leptospira interrogans 1. Undue weight on an obscure culture medium that hasn't been described in any review articles, to my knowledge. Please use secondary sources (review articles), not primary sources. 2. Lengthy descriptions of how antibiotics work is not appropriate. I will keep the one sentence that is worth saving. Tag: Undo
3 November 2022
- 15:0915:09, 3 November 2022 diff hist −94 Applied behavior analysis No reliable source provided Tag: Undo
25 October 2022
- 22:0622:06, 25 October 2022 diff hist −47 Leptospira interrogans →Biology and Biochemistry: It's not known whether L. interrogans requries vitamins B1 and B12. The source does not speak specifically about Leptospira. The experiments with B1 and B12 may have been done with other species of Leptospira. This really belongs in the more general Leptospira article.
- 22:0022:00, 25 October 2022 diff hist −69 Leptospira interrogans →Metabolism/Physiology: Appears to be wp:original research. The source does not say L. interrogans is a strict aerobe. The source does not even say O2 is the sole terminal electron acceptor.
- 21:5521:55, 25 October 2022 diff hist +40 Leptospira interrogans →Disease: Added hatnote before this section gets too bloated.
- 21:5021:50, 25 October 2022 diff hist −576 Leptospira interrogans →Genomics: The first sentence presented info on just one strain, and the second sentence presented info on two strains. Made more general so that genome info is presented for both strains. Removed ref no longer necessary. This really needs to be updated with more recent sources.
- 21:3421:34, 25 October 2022 diff hist −468 Leptospira interrogans →Biology and Biochemistry: Unfortunately, the cited review article from 2011 is out of date. Leptospira has multiple FlaA and FlaB proteins, and where they're located with respect to each other in the flagellum is not known.
- 20:5920:59, 25 October 2022 diff hist −836 Leptospira interrogans →Molecular pathogenesis: This contradicts the first sentence. On the one hand you have a surface adhesin. On the other, this protein that's claimed to be an adhesin is not on the surface. Again, another case of the experiment in the source (inflammation linked to LipL32) not being about what's being claimed (LipL32 being an adhesin)..
- 20:5620:56, 25 October 2022 diff hist −830 Leptospira interrogans →Molecular Pathogenesis: Removed trivial information extracted from a primary source. There's nothing special about a gene with 272 codons having a rho-independent transcription terminator.
- 20:5520:55, 25 October 2022 diff hist +29 Leptospira interrogans Moved stuff related to molecular pathogenesis to its own section, although this really needs a review article since it's a bit controversial.
- 20:5320:53, 25 October 2022 diff hist −9 Leptospira interrogans →Pathogenicity: Titles - replaced unnecessary jargon
- 20:5120:51, 25 October 2022 diff hist −4,651 Leptospira interrogans →Pathogenicity: None of these studies are specific for L. interrogans, and it appears they were conducted in locations where leptospirosis is caused by other species of Leptospira. Also, most of these refs are primary sources. Please use high-quality review articles.
- 20:4020:40, 25 October 2022 diff hist −243 Leptospira interrogans →Human: These numbers for the fatality rate are not specific for Leptospira interrogans. There are other species of Leptospira that cause disease. The one million figure is also wrong - it's one million *severe* cases each year. This illustrates why it's not a good idea to rely on sources that aren't about the claim you're trying to make - this source is a laboratory experiment about L. interrogans exoproteins.
13 October 2022
- 18:0518:05, 13 October 2022 diff hist −1 Leptospira interrogans →top: Replaced "renal" and "hepatic" with terms a layperson can understand.
26 August 2022
- 21:0721:07, 26 August 2022 diff hist 0 Leptospirosis →Pathogenesis: It doesn't make sense to have the lead sentence of the paragraph say that leptospirosis pathogenesis is poorly understood when the rest of the paragraph talks about infection of the reservoir host, which by definition doesn't get leptospirosis. Moved the lead sentence to the second paragraph of the section, where it makes more sense.
- 07:4207:42, 26 August 2022 diff hist +2 Leptospirosis →Molecular tests: Demoted one level
- 07:2807:28, 26 August 2022 diff hist −19 Leptospirosis →Prognosis: Reworded. The ref does not say that persistent symptoms lasted for at least two years in 30% of patients.
- 07:1107:11, 26 August 2022 diff hist −301 Leptospirosis →Pathogenesis: The humoral immune response to LPS has nothing to do with the mechanism of how Lepotspira causes disease.
- 07:1007:10, 26 August 2022 diff hist −1,407 Leptospirosis →Diagnosis: Manual revert. Culture is not used for diagnosis since it takes weeks for bacteria to grow. Neither is molecular typing.
18 August 2022
- 01:4301:43, 18 August 2022 diff hist +52 Lyme disease →LYMErix: Added ages that the vaccine was approved for
- 01:3601:36, 18 August 2022 diff hist +435 Lyme disease →Vaccination: The introductory paragraph to the subsection should mention LYMErix
- 01:2801:28, 18 August 2022 diff hist +20 Lyme disease →LYMErix: Added reference for adjuvant used
- 01:2301:23, 18 August 2022 diff hist −4 Lyme disease →LYMErix: Oops, OspA is a protein
- 01:2101:21, 18 August 2022 diff hist +58 Lyme disease →LYMErix: Needed 3 doses of vaccine to achieve 76% protection; italicized gene name. Adjuvant was aluminum hydroxide.
- 01:1301:13, 18 August 2022 diff hist −21 Lyme disease →LYMErix: The source doesn't say children were protected 100% from Lyme. It says that 100% of children had antibody levels to OspA high enough to be protective, which is a very different statement.
- 01:1101:11, 18 August 2022 diff hist +1 Lyme disease →Vaccination: Moved VLA15 after LYMErix since we already know LYMErix is (somewhat) effective and was sold for a few years; VLA15 is still in the clinical research phase.
25 March 2022
- 18:3718:37, 25 March 2022 diff hist +736 Talk:Applied behavior analysis →Order and hierarchy of subsections of "Use in the treatment of autism spectrum disorders": Reply
24 March 2022
- 01:2901:29, 24 March 2022 diff hist +1 Applied behavior analysis →Use in the treatment of autism spectrum disorders: Moved "Professional concerns" section up
- 01:2401:24, 24 March 2022 diff hist +676 Applied behavior analysis →2020-onward reviews of the efficacy of ABA-based techniques in autism include: New publication in press: Evidence of long-term harm by ABA, a secondary source talking about two surveys of autistics who went through ABA
